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Article

Motor, Somatosensory, Viscerosensory and Metabolic Impairments in a Heterozygous Female Rat Model of Rett Syndrome.

International journal of molecular sciences - 29 Dec 2017

Bhattacherjee Aritra, Winter Michelle K, Eggimann Linda S, Mu Ying, Gunewardena Sumedha, Liao Zhaohui, Christianson Julie A, Smith Peter G

Abstract excerpt

Rett Syndrome (RTT), an autism-related disorder caused by mutation of the X-linked Methyl CpG-binding Protein 2 (MECP2) gene, is characterized by severe cognitive and intellectual deficits. While cognitive deficits are well-documented in humans and rodent models, impairments of sensory, motor and metabolic functions also occur but remain poorly understood. To better understand non-cognitive deficits in RTT, we...

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Identifiers

PMID: 29286317
DOI: 10.3390/ijms19010097
PMCID: PMC5796047

Genes

MECP2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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