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Development of a potent and protective germline-like antibody lineage against Zika virus in a convalescent human

2019-06-05

Abstract excerpt

Zika virus (ZIKV) specific neutralizing antibodies hold a great promise for antibody-based interventions and vaccine design against ZIKV infection. However, their development in infected patients remain unknown. Here, we report on the dynamic development of a potent and protective ZIKV-specific human antibody ZK2B10 initially isolated from a ZIKV convalescent individual using next-generation sequencing (NGS). The...

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Literature Corpus work
1fa2f58e-9701-5c1a-92c9-042b2ad2fa5e
DOI
10.1101/661918
Open publication

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Development of a potent and protective germline-like antibody lineage against Zika virus in a convalescent humanDOI 10.1101/661918
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