Article
The effect of single mutations in Zika virus envelope on escape from broadly neutralizing antibodies.
Journal of virology - 30 Nov 2023
Kikawa Caroline, Cartwright-Acar Catiana H, Stuart Jackson B, Contreras Maya, Levoir Lisa M, Evans Matthew J, Bloom Jesse D, Goo Leslie
Abstract excerpt
IMPORTANCE: The wide endemic range of mosquito-vectored flaviviruses-such as Zika virus and dengue virus serotypes 1-4-places hundreds of millions of people at risk of infection every year. Despite this, there are no widely available vaccines, and treatment of severe cases is limited to supportive care. An avenue toward development of more widely applicable vaccines and targeted therapies is the characterization...
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