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Article

Development of a Potent and Protective Germline-Like Antibody Lineage Against Zika Virus in a Convalescent Human.

Frontiers in immunology - 1 Jan 2019

Gao Fei, Lin Xiaohe, He Linling, Wang Ruoke, Wang Han, Shi Xuanling, Zhang Fuchun, Yin Chibiao, Zhang Linqi, Zhu Jiang, Yu Lei

Abstract excerpt

Zika virus (ZIKV) specific neutralizing antibodies hold great promise for antibody-based interventions and vaccine design against ZIKV infection. However, their development in infected patients remains unclear. Here, we applied next-generation sequencing (NGS) to probe the dynamic development of a potent and protective ZIKV E DIII-specific antibody ZK2B10 isolated from a ZIKV convalescent individual. The unbiased...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31708914
DOI: 10.3389/fimmu.2019.02424
PMCID: PMC6821881

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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