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Article

Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody

22 Apr 2020

Abstract excerpt

Recent epidemics demonstrate the global threat of Zika virus (ZIKV), a flavivirus transmitted by mosquitoes. Although infection is usually asymptomatic or mild, newborns of infected mothers can display severe symptoms, including neurodevelopmental abnormalities and microcephaly. Given the large-scale spread, symptom severity, and lack of treatment or prophylaxis, a safe and effective ZIKV vaccine is urgently...

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PMID: 32321830
DOI: 10.1073/pnas.1919269117

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