Article

Large-scale analysis of B-cell epitopes of envelope: Implications for Zika vaccine and immunotherapeutic development

2019-06-27

Abstract excerpt

<h4>Background: </h4> Cases of the re-emergence of Zika virus in 2015 were associated with severe neurologic complications, including Gillien-Barre syndrome in adults and congenital Zika syndrome in newborns. The major structural determinant of immunity to the Zika virus is the E protein. Although B-cell epitopes of Zika E protein were recently identified, data regarding epitope variations among Zika strains in pr...

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Literature Corpus work: 8671ffdd-ca20-52a0-8900-84b85ae16ef0
DOI: 10.12688/f1000research.16454.2

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