Article
Ifitm3 limits the severity of acute influenza in mice.
PLoS pathogens - 1 Sept 2012
Bailey Charles C, Huang I-Chueh, Kam Christina, Farzan Michael
Abstract excerpt
Interferon-induced transmembrane (IFITM) proteins are a family of viral restriction factors that inhibit the entry processes of several pathogenic viruses, including influenza A virus (IAV), in vitro. Here we report that IAV-infected knockout mice lacking the Ifitm locus on chromosome 7 exhibited...
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