Article

Dual Palmitoylation of PRCD, a Photoreceptor-Specific Protein Linked to RP, Alters Protein Stability and Subcellular Localization

2022-05-30

Abstract excerpt

Progressive rod-cone degeneration (PRCD) is a photoreceptor outer segment (POS) disc-specific protein essential for maintaining outer segment (OS) structures, while also contributing to rhodopsin packaging densities and distribution in the disc membranes. Previously, we showed PRCD undergoing palmitoylation at the sole cysteine (Cys2), where a mutation is found linked with retinitis pigmentosa (RP) that is crucial...

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Literature Corpus work: 1f49236d-2555-5cda-8397-659f606ff4a3
DOI: 10.1101/2022.05.30.494045

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