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Article

Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration.

Journal of proteome research - 7 Jun 2013

Skiba Nikolai P, Spencer William J, Salinas Raquel Y, Lieu Eric C, Thompson J Will, Arshavsky Vadim Y

Abstract excerpt

Visual signal transduction takes place on the surface of flat membrane vesicles called photoreceptor discs, which reside inside the light-sensitive outer segment organelle of vertebrate photoreceptor cells. Although biochemical studies have indicated that discs are built with a handful of highly specialized proteins, proteomic studies have yielded databases consisting of hundreds of entries. We addressed this...

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Identifiers

PMID: 23672200
DOI: 10.1021/pr4003678
PMCID: PMC3771658

Genes

PRCD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration.PMID 23672200Read ↗

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