Aberrant protein trafficking in retinal degenerations: The initial phase of retinal remodeling.

doi:10.1016/j.exer.2015.11.007

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Article

Aberrant protein trafficking in retinal degenerations: The initial phase of retinal remodeling.

Experimental eye research - 1 Sept 2016

Bales Katie L, Gross Alecia K

Abstract excerpt

Retinal trafficking proteins are involved in molecular assemblies that govern protein transport, orchestrate cellular events involved in cilia formation, regulate signal transduction, autophagy and endocytic trafficking, all of which if not properly controlled initiate retinal degeneration. Improper function and or trafficking of these proteins and molecular networks they are involved in cause a detrimental...

Topics

Animals
Cell Death
Cell Movement
Humans
Mutation
Photoreceptor Cells, Vertebrate
Protein Transport
Retina
Retinal Degeneration
Rhodopsin
Signal Transduction

Source

Open in PubMed Open full text

Identifiers

PMID: 26632497
DOI: 10.1016/j.exer.2015.11.007
PMCID: PMC4882275

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