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Article

Palmitoylation stabilizes unliganded rod opsin.

Proceedings of the National Academy of Sciences of the United States of America - 4 May 2010

Maeda Akiko, Okano Kiichiro, Park Paul S-H, Lem Janis, Crouch Rosalie K, Maeda Tadao, Palczewski Krzysztof

Abstract excerpt

S-palmitoylation is a conserved feature in many G protein-coupled receptors (GPCRs) involved in a broad array of signaling processes. The prototypical GPCR, rhodopsin, is S-palmitoylated on two adjacent C-terminal Cys residues at its cytoplasmic surface. Surprisingly, absence of palmitoylation ha...

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Identifiers

PMID: 20404157
DOI: 10.1073/pnas.1000640107
PMCID: PMC2889565

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20404157-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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