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Article

PRCD-associated retinitis pigmentosa in dogs and humans.

Experimental eye research - 1 Aug 2026

Dufour Valerie L, Sato Yu, Sumaroka Alexander, Sudharsan Raghavi, Banin Eyal, Yu Yinxi, Ripolles-Garcia Ana, Kwok Jennifer C, Aleman Tomas S, Ying Gui-Shuang, Sharon Dror, Cideciyan Artur V, Beltran William A, Aguirre Gustavo D

Abstract excerpt

PRCD is a ∼6 kDa protein localized to the cytosolic surface of rod and cone outer segment discs. Pathogenic variants in the PRCD gene cause autosomal recessive retinal degeneration in human patients and in over 65 dog breeds. We characterized the natural history and phenotype of PRCD-associated retinal disease in dogs and compared it with the human condition. Human patients with PRCD-associated retinitis...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 42107853
DOI: 10.1016/j.exer.2026.111045
PMCID: PMC13370655

Genes

PRCD

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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