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Article

PRCD Is a Small Disc-Specific Rhodopsin-Binding Protein of Unknown Function.

Advances in experimental medicine and biology - 1 Jan 2019

Spencer William J, Arshavsky Vadim Y

Abstract excerpt

PRCD (progressive rod-cone degeneration) is a small ~6 kDa protein with unknown function that specifically resides in photoreceptor discs and interacts with rhodopsin. PRCD's discovery resulted from decades-long study of a canine retinal disease called progressive rod-cone degeneration which is one of the most frequent causes of blindness in dogs characterized by the slow, progressive death of rod photoreceptors...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 31884666
DOI: 10.1007/978-3-030-27378-1_87

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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PRCD Is a Small Disc-Specific Rhodopsin-Binding Protein of Unknown Function.PMID 31884666Read ↗

PRCD-associated retinitis pigmentosa in dogs and humans.Semantic proximity Read ↗

Identification of a novel mutation in the PRCD gene causing autosomal recessive retinitis pigmentosa in a Turkish family.Semantic proximity Read ↗

The progressive rod-cone degeneration (PRCD) protein is secreted through the conventional ER/Golgi-dependent pathway.Semantic proximity Read ↗

Linkage analysis and comparative mapping of canine progressive rod-cone degeneration (prcd) establishes potential locus homology with retinitis pigmentosa (RP17) in humans.Semantic proximity Read ↗

Dual Palmitoylation of PRCD, a Photoreceptor-Specific Protein Linked to RP, Alters Protein Stability and Subcellular LocalizationSemantic proximity Read ↗

PRCD is essential for high-fidelity photoreceptor disc formationSemantic proximity Read ↗

R17C Mutation in Photoreceptor Disc-Specific Protein, PRCD, Results in Additional Lipidation Altering Protein Stability and Subcellular Localization.Semantic proximity Read ↗

Proteomic identification of unique photoreceptor disc components reveals the presence of PRCD, a protein linked to retinal degeneration.Semantic proximity Read ↗

Dynamics of the rhomboid-like protein RHBDD2 expression in mouse retina and involvement of its human ortholog in retinitis pigmentosa.Semantic proximity Read ↗

Cellular and Molecular Mechanisms of Pathogenesis Underlying Inherited Retinal Dystrophies.Semantic proximity Read ↗

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Aberrant protein trafficking in retinal degenerations: The initial phase of retinal remodeling.Semantic proximity Read ↗

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