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<i>Castling</i> , a novel therapeutic concept for rewiring pathological gene-expression networks, enabled by the TRIPLE technology

2026-01-30

Abstract excerpt

Pathological conditions often arise from dysregulation of complex gene networks, with microRNAs (miRNAs) acting as central modulators. Disease progression is frequently characterized by upregulation of “disease-promoting” miRNA, suppressing beneficial pathways, and concomitant downregulation of “protective/therapeutic” miRNAs, normally restraining pathological programs. Since individual miRNAs coordinately regulat...

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Literature Corpus work
1f164aa3-894b-5ecd-b6ab-8ccdcdb96acc
DOI
10.64898/2026.01.28.702195
Open publication

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<i>Castling</i> , a novel therapeutic concept for rewiring pathological gene-expression networks, enabled by the TRIPLE technologyDOI 10.64898/2026.01.28.702195
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