Article

Rewiring Cancer Drivers to Activate Apoptosis

2022-12-07

Abstract excerpt

<h4>ABSTRACT</h4> Genes that drive the proliferation, survival, invasion and metastasis of malignant cells have been identified for many human cancers 1–6 . Independent studies have identified cell death pathways that eliminate cells for the good of the organism 7–10 . The coexistence of the cell death pathways with the driver mutations suggest that the cancer driver could be rewired to activate cell death. We...

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Literature Corpus work: 185e9c87-7ede-59c4-8b56-6c68f23a6cc2
DOI: 10.1101/2022.12.04.517548

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