Article

Using gene genealogies to localize rare variants associated with complex traits in diploid populations

2017-09-07

Abstract excerpt

<h4>Background and Aims</h4> Many methods can detect trait association with causal variants in candidate genomic regions; however, a comparison of their ability to localize causal variants is lacking. We extend a previous study of the detection abilities of these methods to a comparison of their localization abilities. <h4>Methods</h4> Through coalescent simulation, we compare several popular association methods...

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Literature Corpus work: 1f06be14-c6cf-5101-a261-f2964a7ae2a5
DOI: 10.1101/182345

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