Clade distillation for genome-wide association studies.

Abstract excerpt

Testing inferred haplotype genealogies for association with phenotypes has been a longstanding goal in human genetics given their potential to detect association signals driven by allelic heterogeneity-when multiple causal variants modulate a phenotype-in both coding and noncoding regions. Recent scalable methods for inferring locus-specific genealogical trees along the genome, or representations thereof, have...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Algorithms
• Share to Genome-Wide Association Study
• Share to Haplotypes