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Article

Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architecture

2021-04-19

Abstract excerpt

Most cancers are characterized by the somatic acquisition of genomic rearrangements during tumour evolution that eventually drive the oncogenesis. There are different mutational mechanisms causing structural variation, some of which are specific to particular cancer types. Here, using multiplatform sequencing technologies, we identify and characterize a remarkable mutational mechanism in human hepatocellular carci...

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Identifiers and source

Literature Corpus work
1f038c48-14c2-5d1d-8b3d-07ac6114d584
DOI
10.1101/2021.04.19.440412
Open publication

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Aberrant integration of Hepatitis B virus DNA promotes major restructuring of human hepatocellular carcinoma genome architectureDOI 10.1101/2021.04.19.440412
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