Article

Functional buffering via cell-specific gene expression promotes tissue homeostasis and cancer robustness

2021-07-27

Abstract excerpt

Functional buffering that ensures biological robustness is critical for maintaining tissue homeostasis, organismal survival, and evolution of novelty. However, the mechanism underlying functional buffering, particularly in multicellular organisms, remains largely elusive. Here, we developed an inference index (C-score) for Cell-specific Expression- BUffering (CEBU), whereby functional buffering is mediated via exp...

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Literature Corpus work: 1ecbdefd-148c-50d2-b3b8-e7995459859c
DOI: 10.1101/2021.07.26.453775

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