Article

Comprehensive patient-level classification and quantification of driver events in TCGA PanCanAtlas cohorts

2021-03-18

Abstract excerpt

There is a growing need to develop novel therapeutics for targeted treatment of cancer. The prerequisite to success is the knowledge about which types of molecular alterations are predominantly driving tumorigenesis. To shed light onto this subject, we have utilized the largest database of human cancer mutations – TCGA PanCanAtlas, multiple established algorithms for cancer driver prediction (2020plus, CHASMplus,...

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Literature Corpus work: 1ec73824-af9c-5741-bf40-38b55f1f1a45
DOI: 10.1101/2021.03.17.435828

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