Back to search

Article

Pan-cancer detection of driver genes at the single-patient resolution

2020-06-12

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Identifying the complete repertoire of genes that drive cancer in individual patients is crucial for precision oncology. Most established methods identify driver genes that are recurrently altered across patient cohorts. However, mapping these genes back to patients leaves a sizeable fraction with few or no drivers, hindering our understanding of cancer mechanisms and limiti...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
af743937-7902-5b0f-a0cd-3df1f0cc07e7
DOI
10.1101/2020.06.12.147983
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Pan-cancer detection of driver genes at the single-patient resolutionDOI 10.1101/2020.06.12.147983
Select a neighboring publication to make it the new centre.