Article

Whole-exome sequencing identifies a CD38 variant in a Chinese family with Hodgkin’s lymphoma

2024-02-09

Abstract excerpt

<title>Abstract</title> <p> Hodgkin’s lymphoma (HL) exhibits genetic susceptibility, but little is known about the pathogenic genes associated with the disease. Here, we present a case of two siblings from a consanguineous Chinese family who were both diagnosed with nodular sclerosis classical HL. The sister and brother were diagnosed at the ages of 22 and 29, respectively, both presenting with involvement of th...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1eb22c07-2fd3-5068-8fd0-88a10723ae88
DOI: 10.21203/rs.3.rs-3923763/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Whole-exome sequencing identifies a CD38 variant in a Chinese family with Hodgkin’s lymphomaDOI 10.21203/rs.3.rs-3923763/v1Read

Identification of Familial Hodgkin Lymphoma Predisposing Genes Using Whole Genome SequencingSemantic proximity Read

A genome-wide association study of Hodgkin's lymphoma identifies new susceptibility loci at 2p16.1 (REL), 8q24.21 and 10p14 (GATA3).Semantic proximity Read

Bio-informatic Analysis of Missense Single Nucleotide Polymorphisms (SNPs) in Human CD38 Gene Associated with B-Chronic Lymphocytic LeukemiaSemantic proximity Read

Whole exome sequencing in families at high risk for Hodgkin lymphoma: identification of a predisposing mutation in the KDR gene.Semantic proximity Read

Whole-genome Sequencing of Reed-sternberg Cells Identifies Outcome Determinants in Hodgkin LymphomaSemantic proximity Read

Ultra-Deep Sequencing Reveals the Mutational Landscape of Classical Hodgkin LymphomaSemantic proximity Read

Functional multigenic variations associated with hodgkin lymphoma.Semantic proximity Read

Discovery of novel predisposing coding and noncoding variants in familial Hodgkin lymphoma.Semantic proximity Read

CD38 gene polymorphisms contribute to genetic susceptibility to B-cell chronic lymphocytic leukemia: evidence from two case-control studies in Polish Caucasians.Semantic proximity Read

Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility.Semantic proximity Read

A Novel Risk Locus at 6p21.3 for Epstein-Barr Virus-Positive Hodgkin Lymphoma.Semantic proximity Read

Exome sequencing reveals germline NPAT mutation as a candidate risk factor for Hodgkin lymphoma.Semantic proximity Read