Article
Conditional eQTL analysis reveals allelic heterogeneity of gene expression.
Human molecular genetics - 15 Apr 2017
Jansen Rick, Hottenga Jouke-Jan, Nivard Michel G, Abdellaoui Abdel, Laport Bram, de Geus Eco J, Wright Fred A, Penninx Brenda W J H, Boomsma Dorret I
Abstract excerpt
In recent years, multiple eQTL (expression quantitative trait loci) catalogs have become available that can help understand the functionality of complex trait-related single nucleotide polymorphisms (SNPs). In eQTL catalogs, gene expression is often strongly associated with multiple SNPs, which may reflect either one or multiple independent associations. Conditional eQTL analysis allows a distinction between...
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