Article

Ezh2 as an epigenetic checkpoint regulator during monocyte differentiation: a potential target to improve cardiac repair after myocardial infarction

2021-03-12

Abstract excerpt

<title>Abstract</title> <p>Epigenetic regulation of histone H3K27 methylation has recently emerged as a key step during alternative M2-like macrophage polarization, essential for cardiac repair after Myocardial Infarction (MI). We hypothesized that EZH2, responsible for H3K27 methylation, could act as an epigenetic checkpoint regulator during this process. We demonstrate for the first-time an EZH2 ectopic, and pu...

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Literature Corpus work: 1e991340-265f-5fc0-ad3f-acfc09e2a38d
DOI: 10.21203/rs.3.rs-263770/v1

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