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Article

Overlap in genetic risk for cross-disorder vulnerability to mental disorders and genetic risk for altered subcortical brain volumes.

Journal of affective disorders - 1 Mar 2021

Campbell Megan, Jahanshad Neda, Mufford Mary, Choi Karmel W, Lee Phil, Ramesar Raj, Smoller Jordan W, Thompson Paul, Stein Dan J, Dalvie Shareefa

Abstract excerpt

BACKGROUND: There have been considerable recent advances in understanding the genetic architecture of psychiatric disorders as well as the underlying neurocircuitry. However, there is little work on the concordance of genetic variations that increase risk for cross-disorder vulnerability, and those that influence subcortical brain structures. We undertook a genome-wide investigation of the genetic overlap between...

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Identifiers

PMID: 33601715
DOI: 10.1016/j.jad.2020.12.062

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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