Article

Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome

2022-09-02

Abstract excerpt

Tourette Syndrome (TS) is a complex neurodevelopmental disorder characterized by vocal and motor tics lasting more than a year. It is highly polygenic in nature with both rare and common previously associated variants. Epidemiological studies have shown TS to be correlated with other phenotypes, but large-scale phenome wide analyses in biobank level data have not been performed to date. In this study, we used the...

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Literature Corpus work: 66799cc0-0e48-59aa-934f-de91b99aae5c
DOI: 10.1101/2022.09.01.22279340

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