Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome

Abstract excerpt

Tourette Syndrome (TS) is a complex neurodevelopmental disorder characterized by vocal and motor tics lasting more than a year. It is highly polygenic in nature with both rare and common previously associated variants. Epidemiological studies have shown TS to be correlated with other phenotypes, but large-scale phenome wide analyses in biobank level data have not been performed to date. In this study, we used the...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Cardiovascular Effects of Exercise
• Share to Genetic Associations and Epidemiology
• Share to Obsessive-Compulsive Spectrum Disorders