Article

Genome-wide molecular recording using Live-seq

2021-03-24

Abstract excerpt

Single-cell transcriptomics (scRNA-seq) has greatly advanced our ability to characterize cellular heterogeneity in health and disease. However, scRNA-seq requires lysing cells, which makes it impossible to link the individual cells to downstream molecular and phenotypic states. Here, we established Live-seq, an approach for single-cell transcriptome profiling that preserves cell viability during RNA extraction usi...

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Literature Corpus work: 647c9c0f-3ae9-5f71-9ca4-8021657e7aa9
DOI: 10.1101/2021.03.24.436752

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