Article

Evaluation of K18- <i>hACE2</i> mice as a model of SARS-CoV-2 infection

2020-06-26

Abstract excerpt

<h4>Abstract/Summary</h4> Murine models of SARS-CoV-2 infection are critical for elucidating the biological pathways underlying COVID-19 disease. Because human ACE2 is the receptor for SARS-CoV-2, mice expressing the human ACE2 gene have shown promise as a potential model for COVID-19. Five mice from the transgenic mouse strain K18- hACE2 were intranasally inoculated with SARS-CoV-2 Hong Kong/VM20001061/2020. M...

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Literature Corpus work: 1e0a60ca-a75a-5683-b116-1b08a3388cdb
DOI: 10.1101/2020.06.26.171033

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