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Generation and characterization of a humanized ACE2 mouse model to study long‐term impacts of SARS‐CoV‐2 infection

1 Jan 2024

Abstract excerpt

Abstract Although the COVID‐19 pandemic has officially ended, the persistent challenge of long‐COVID or post‐acute COVID sequelae (PASC) continues to impact societies globally, highlighting the urgent need for ongoing research into its mechanisms and therapeutic approaches. Our team has recently developed a novel humanized ACE2 mouse model (hACE2ki) designed explicitly for long‐COVID/PASC research. This model...

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PMID: 38185937
DOI: 10.1002/jmv.29349

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