Article

Transferability and accuracy of electronic health record-based predictors compared to polygenic scores

2024-10-08

Abstract excerpt

Electronic health record (EHR)-based phenotype risk scores (PheRS) leverage individuals’ health trajectories to infer disease risk. Similarly, polygenic scores (PGS) use genetic information to estimate disease risk. While PGS generalizability has been previously studied, less is known about PheRS transferability across healthcare systems and whether PheRS provide complementary risk information to PGS. We trained P...

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Literature Corpus work: 1e043f07-6395-5cde-8285-12c31947dca6
DOI: 10.1101/2024.10.08.24315073

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