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The role of macrophage plasticity in neurodegenerative diseases

12 Aug 2024

Abstract excerpt

Tissue-resident macrophages and recruited macrophages play pivotal roles in innate immunity and the maintenance of brain homeostasis. Investigating the involvement of these macrophage populations in eliciting pathological changes associated with neurodegenerative diseases has been a focal point of research. Dysregulated states of macrophages can compromise clearance mechanisms for pathological proteins such as...

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PMID: 39135084
DOI: 10.1186/s40364-024-00624-7

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