Article

Simultaneous analysis of single-cell gene expression and morphology provides new insight into how microglia change with age

2025-03-01

Abstract excerpt

Cellular morphology is intimately connected with function. While the link between morphology and functional states has been studied extensively, the role of subcellular transcript localization in cellular function remains unclear. Here we use microglia, the brain’s resident macrophages, as a model to dissect the interaction of morphology, transcript localization, and function. Using multiplexed error-robust fluore...

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Literature Corpus work: c53c8e41-1ef3-5ad0-b5cb-f97e858aebf5
DOI: 10.1101/2025.02.28.640888

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