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Article

Arrhythmia Mechanisms and Spontaneous Calcium Release: I - Multi-scale Modelling Approaches

2018-10-03

Abstract excerpt

<h4>Motivation</h4> Spontaneous sub-cellular calcium release events (SCRE), controlled by microscopic stochastic fluctuations of the proteins responsible for intracellular calcium release, are conjectured to promote the initiation and perpetuation of rapid arrhythmia associated with conditions such as heart failure and atrial fibrillation: SCRE may underlie the emergence of spontaneous excitation in single cells,...

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Literature Corpus work
1dea3fcd-f16e-511d-a30d-e63987fd80d8
DOI
10.1101/434464
Open publication

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Arrhythmia Mechanisms and Spontaneous Calcium Release: I - Multi-scale Modelling ApproachesDOI 10.1101/434464
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