Article

<i>In Silico</i> Optimisation of Regenerative Cell Therapy in the Infarcted Human Ventricles to Mitigate Arrhythmic Burden

2025-10-05

Abstract excerpt

Myocardial infarction remains a frequent cause of heart failure and mortality. Cell therapy has been shown promising in pre-clinical trials to regenerate the damaged tissue, but delivered cells may beat spontaneously and produce arrhythmias in the ventricles, particularly in the first weeks after delivery, which hinders clinical application. Previous studies have proposed ionic targets to supress the cells’ automa...

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Literature Corpus work: e85a680a-33f2-5ff6-bebd-775ef400a2e8
DOI: 10.1101/2025.10.03.680241

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