Article

Fibroblast Density is a Risk Factor for Drug-induced Arrhythmias

2025-01-22

Abstract excerpt

A recent study by Kawatou et al . has shown that the local heterogeneity of ion channel conductance is a critical substrate for focal or reentrant arrhythmias. However, the role of fibroblasts with repolarization heterogeneity in the initiation and maintenance of arrhythmias remains unknown. In this study, we investigated how diffuse fibrosis contributes to the formation of focal and reentrant arrhythmias under d...

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Literature Corpus work: 8bddcc00-b7d8-5b2c-9731-07df7e529398
DOI: 10.1101/2025.01.19.633080

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