Article

Single cell transcriptomic heterogeneity in invasive ductal and lobular breast cancer cells

2020-02-23

Abstract excerpt

Invasive lobular breast carcinoma (ILC), one of the major breast cancer histological subtypes, exhibits unique clinical and molecular features compared to the other well-studied ductal cancer subtype (IDC). The pathognomonic feature of ILC is loss of E-cadherin, mainly caused by inactivating mutations within the CDH1 gene, but the extent of contribution of this genetic alteration to ILC-specific molecular charact...

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Literature Corpus work: 15651eeb-5598-5a86-a36a-b9ede00097ac
DOI: 10.1101/2020.02.21.959023

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