Article

Palmitic acid inhibits vascular smooth muscle cell switch to synthetic phenotype through upregulation of miR-22 expression

2022-09-27

Abstract excerpt

<h4>Background: </h4> Vascular smooth muscle cell (VSMC) phenotype switch to a dedifferentiated, synthetic phenotype has been shown to play a vital role in many vascular diseases. Mounting evidence has shown that fatty acid metabolism is highly associated with vascular diseases. However, how fatty acids regulate VSMC phenotype is poorly understood. Here, we aimed to examine the effects of palmitic acid (PA), the m...

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Literature Corpus work: 1d8ceda4-a796-5e20-928c-fbaf93976a3e
DOI: 10.21203/rs.3.rs-1852465/v1

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