Article
Six Shades of Vascular Smooth Muscle Cells Illuminated by KLF4 (Krüppel-Like Factor 4).
Arteriosclerosis, thrombosis, and vascular biology - 1 Nov 2021
Yap Carmen, Mieremet Arnout, de Vries Carlie J M, Micha Dimitra, de Waard Vivian
Abstract excerpt
Multiple layers of vascular smooth muscle cells (vSMCs) are present in blood vessels forming the media of the vessel wall. vSMCs provide a vessel wall structure, enabling it to contract and relax, thus modulating blood flow. They also play a crucial role in the development of vascular diseases, such as atherosclerosis and aortic aneurysm formation. vSMCs display a remarkable high degree of plasticity. At present,...
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