Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LncRNA MFRL regulates the phenotypic switch of vascular smooth muscle cells to attenuate arterial remodeling by encoding a novel micropeptide MFRLP.

Translational research : the journal of laboratory and clinical medicine - 1 Oct 2024

Liu Xiaocong, Chen Siyu, Luo Wei, Yu Chen, Yan Shaohua, Lei Li, Qiu Shifeng, Lin Xinxin, Feng Ting, Shi Jinglin, Zhang Qiuxia, Liang Hongbin, Liu Xuewei, Lee Alex Pui-Wai, Zheng Lei, Zhang Xinlu, Xiu Jiancheng

Abstract excerpt

BACKGROUND: Arterial remodeling is a common pathophysiological change in the pathogenesis of cardiovascular diseases in which the phenotypic switch of vascular smooth muscle cells (VSMC) plays an important role. Recently, an increasing number of long non-coding RNAs(lncRNAs) have been shown to encode micropeptides that play biological roles and have great clinical transformation potential. However, the role of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related molecular mechanisms research
Share to Mitophagy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Muscle, Smooth, Vascular

Share to Myocytes, Smooth Muscle

Share to Phenotype

Share to Reactive Oxygen Species

Share to RNA, Long Noncoding

Share to Vascular Remodeling

Source

Identifiers

PMID: 38838852
DOI: 10.1016/j.trsl.2024.05.009

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LncRNA MFRL regulates the phenotypic switch of vascular smooth muscle cells to attenuate arterial remodeling by encoding a novel micropeptide MFRLP.PMID 38838852Read ↗

How vascular smooth muscle cell phenotype switching contributes to vascular disease.Semantic proximity Read ↗

Elucidating VSMC phenotypic transition mechanisms to bridge insights into cardiovascular disease implicationsSemantic proximity Read ↗

LncRNA PSR Regulates Vascular Remodeling Through Encoding a Novel Protein Arteridin.Semantic proximity Read ↗

Long non-coding RNAs at the crossroad of vascular smooth muscle cell phenotypic modulation in atherosclerosis and neointimal formation.Semantic proximity Read ↗

Exosomes: mediators regulating the phenotypic transition of vascular smooth muscle cells in atherosclerosis.Semantic proximity Read ↗

An overview of potential molecular mechanisms involved in VSMC phenotypic modulation.Semantic proximity Read ↗

Six Shades of Vascular Smooth Muscle Cells Illuminated by KLF4 (Krüppel-Like Factor 4).Semantic proximity Read ↗

Arterial remodeling: the role of mitochondrial metabolism in vascular smooth muscle cells.Semantic proximity Read ↗

Noncoding RNAs in smooth muscle cell homeostasis: implications in phenotypic switch and vascular disorders.Semantic proximity Read ↗

Research progress on the mechanism of phenotypic transformation of pulmonary artery smooth muscle cells induced by hypoxiaSemantic proximity Read ↗

Transcriptomics analysis of long non-coding RNAs in smooth muscle cells from patients with peripheral artery disease and diabetes mellitusSemantic proximity Read ↗

MTMR7 suppresses the phenotypic switching of vascular smooth muscle cell and vascular intimal hyperplasia after injury via regulating p62/mTORC1-mediated glucose metabolismSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.