Article

Computational structure prediction methods enable the systematic identification of oncogenic mutations

2022-11-20

Abstract excerpt

Oncogenic mutations are associated with the activation of key pathways necessary for the initiation, progression and treatment-evasion of tumors. While large genomic studies provide the opportunity of identifying these mutations, the vast majority of variants have unclear functional roles presenting a challenge for the use of genomic studies in the clinical/therapeutic setting. Recent developments in predicting pr...

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Literature Corpus work: 1d6f0241-b741-5f88-a332-f1db499090bb
DOI: 10.1101/2022.11.18.517015

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