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Article

Assessment of the bidirectional causal association between frailty and depression: A Mendelian randomization study

5 Sept 2023

Abstract excerpt

BACKGROUND: Observational studies have demonstrated a strong bidirectional association between frailty and depression, but it remains unclear whether this association reflects causality. This study aimed to examine the bidirectional causal relationship between frailty and depression. METHODS: Using genome-wide association study summary data, two-sample Mendelian randomization was performed to test for the...

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Chronic Disease Management Strategies
Frailty in Older Adults
Genetic Associations and Epidemiology

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37670569
DOI: 10.1002/jcsm.13319

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