Article
Biology of frailty: Modulation of ageing genes and its importance to prevent age-associated loss of function.
Molecular aspects of medicine - 1 Aug 2016
Viña Jose, Tarazona-Santabalbina Francisco Jose, Pérez-Ros Pilar, Martínez-Arnau Francisco Miguel, Borras Consuelo, Olaso-Gonzalez Gloria, Salvador-Pascual Andrea, Gomez-Cabrera Mari Carmen
Abstract excerpt
Frailty is associated with loss of functional reserve as well as with the prediction of adverse events in the old population. The traditional criteria of frailty are based on five physical determinations described in the Cardiovascular Health Study. We propose that biological and genetic markers of frailty should be used to increase the predictive capacity of the established clinical indeces. In recent times,...
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