Article

LGR6 is necessary for attaining peak bone mass and regulates osteogenesis through differential ligand use

2021-07-16

Abstract excerpt

<h4>ABSTRACT</h4> Leucine-rich repeat containing G-protein-coupled receptor 6 (LGR6) is a marker of osteoprogenitor cells and is dynamically expressed during in vitro osteodifferentation of mouse and human mesenchymal stem cells (MSCs). While the Lgr6 genomic locus has been associated with osteoporosis in human cohorts, the precise molecular function of LGR6 in osteogenesis and maintenance of bone mass are not ye...

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Literature Corpus work: 1d4112a5-1461-5825-a2db-699b635417aa
DOI: 10.1101/2021.07.16.452698

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