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Role of Leucine-Rich Repeat–Containing G-Protein-Coupled Receptors 4–6 (LGR4–6) in the Ovary and Other Female Reproductive Organs: A Literature Review

1 Jan 2025

Abstract excerpt

Leucine-rich repeat-containing G-protein-coupled receptors regulate stem cell activity and tissue homeostasis within female reproductive organs, primarily through their interaction with the Wnt/β-catenin signaling pathway. LGR4-6 are increasingly recognized for their roles in organ development, regeneration, and cancer. This review aims to provide a comprehensive overview of the roles of LGR4-6 in female...

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PMID: 39874091
DOI: 10.1177/09636897241303441

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