Article

Advanced Cardiac Organoid Model for Studying Doxorubicin-Induced Cardiotoxicity

2025-05-08

Abstract excerpt

Cardiac organoids provide an in vitro platform for studying heart disease mechanisms and drug responses. However, a major limitation is the immaturity of cardiomyocytes, restricting their ability to mimic adult cardiac physiology. Additionally, the inadequacy of commonly used extracellular matrices (ECM), which fail to replicate the biochemical and mechanical properties of natural heart tissue, poses significant c...

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Literature Corpus work: 1d2c63d5-719e-58cf-92c9-2e4f3f00831e
DOI: 10.1101/2025.05.02.651878

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