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Article

Molecular Profiles of Brain Metastases: A Focus on Heterogeneity

28 May 2021

Abstract excerpt

Brain metastasis is a common and devastating clinical entity. Intratumor heterogeneity in brain metastases poses a crucial challenge to precision medicine. However, advances in next-generation sequencing, new insight into the pathophysiology of driver mutations, and the creation of novel tumor models have allowed us to gain better insight into the genetic landscapes of brain metastases, their temporal evolution,...

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PMID: 34071176
DOI: 10.3390/cancers13112645

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