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A CD45RO+ stem cell memory T cell population intermediate to canonical stem cell memory and central memory T cells in human cancer.

2022-02-03

Abstract excerpt

<title>Abstract</title> <p>T memory stem cells (Tscm) are integral for effective immunotherapy and antitumor responses, but little is known about Tscm immunobiology in solid human tumors. Here we identify self-renewing and multipotent Tscm tumor-infiltrating lymphocytes (TILs) in human cancer and present a novel Tscm subset which expresses CD45RO, is derived from CD45RO- Tscm T cells, and is capable of self-renew...

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Literature Corpus work
1cbf7520-204b-5cd9-8e26-72c1e5fd4d03
DOI
10.21203/rs.3.rs-1296773/v1
Open publication

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A CD45RO+ stem cell memory T cell population intermediate to canonical stem cell memory and central memory T cells in human cancer.DOI 10.21203/rs.3.rs-1296773/v1
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