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Memory T cells: strategies for optimizing tumor immunotherapy

27 Mar 2020

Abstract excerpt

Several studies have demonstrated that memory T cells including stem cell memory (Tscm) T cells and central memory (Tcm) T cells show superior persistence and antitumor immunity compared with effector memory T (Tem) cells and effector T (Teff) cells. Furthermore, the Tcm/Teff ratio has been reported to be a predictive biomarker of immune responses against some tumors. Thus, a system-level understanding of the...

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PMID: 32221812
DOI: 10.1007/s13238-020-00707-9

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