Article

Supplementary Elevated triglycerides predispose patients to aortic dissection by increasing inflammasome-induced pyroptosis

2024-01-16

Abstract excerpt

Aortic dissection (AD) is an acute and life-threatening disease that requires invasive therapy once the aorta has been lacerated. Although several studies have suggested that abnormal lipid metabolism is associated with the development of AD, there are no studies examining the specific mechanisms by which abnormal lipid metabolism contributes to the development of aortic dissection. The aim of this study was to in...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1ca48f69-a23e-5cb7-a115-58cf4633ab83
DOI: 10.21203/rs.3.rs-3862539/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Supplementary Elevated triglycerides predispose patients to aortic dissection by increasing inflammasome-induced pyroptosisDOI 10.21203/rs.3.rs-3862539/v1Read

Lactylation associated biomarkers and immune infiltration in aortic dissectionSemantic proximity Read

A Vascular Dissection and Rupture Linked Metabolite Acts Via BLT2 ReceptorSemantic proximity Read

Lack of evidence for the involvement of non-canonical pyroptosis in a mouse model of thoracic aortic dissection.Semantic proximity Read

Integrative mediation and multi-omics analysis to decode Aortic dissection’s genetic causal phenotype and potential therapeutic targetsSemantic proximity Read

Macrophage metabolic reprogramming aggravates aortic dissection through the HIF1α-ADAM17 pathway✰Semantic proximity Read

Exaggerated Autophagy in Stanford Type A Aortic Dissection: A Transcriptome Pilot Analysis of Human Ascending Aortic TissuesSemantic proximity Read

Single-Cell RNA Sequencing Reveals Cellular Heterogeneity and Protective Effects of Fenofibrate in Acute Type A Aortic DissectionSemantic proximity Read

A novel non-genetic murine model of hyperglycemia and hyperlipidemia-associated aggravated atherosclerosisSemantic proximity Read

Circulating APOH promotes aortic dissection by activating the vascular smooth muscle cell NR5A1–PPARγ pathwaySemantic proximity Read

Transcriptome Insights into Protective Mechanisms of Ferroptosis Inhibition in Aortic DissectionSemantic proximity Read

Hypertriglyceridemia as a Key Contributor to Abdominal Aortic Aneurysm Development and Rupture: Insights from Genetic and Experimental ModelsSemantic proximity Read

Uncovering Druggable Targets in Aortic Dissection: An Association Study Integrating Mendelian Randomization, pQTL, and Protein–Protein Interaction NetworkSemantic proximity Read